Review

Histamine Background

Histamine Knockouts

Behavioural stuff with feeding etc

Uncoupling Proteins etc???

The different histamine receptors

H1
H2 - no implication in feeding by selective agonists/antagonists
H3 - presynaptic ?auto or hetero? receptor, antagonism leads to increased histamine release

Histamine and AAPDs

Histamine and Leptin

Histamine and Taste Mechanisms

Histamine and Circadian Misalignment

Histamine and the period genes

Effect on expression outside of SCN
Relate to research by Turek and Marcheva

Pharmacology of Histamine Receptors

Histamine and Thermoregulation