#**causes of disease** ##**pathogens** *1)what they are,2) how they get into the body & 3) how they cause disease* **1) pathogen:** any micro-organism that causes disease. (*pathogens include bacteria, viruses & fungi)* **2) gas exchange system:** many pathogens enter the body through the gas exchange surfaces. pathogens that cause influenza, tuberculosis & bronchitis infect in this way. **2) digestive system:** food & water may carry pathogens into the stomach & intestines via the mouth. cholera, typhoid & dysentery pathogens enter by this means. **3) By damaging host tissue:** numbers can cause damage, some break down the membranes, viruses can take over the DNA and RNA of hosts. **3) by producing toxins:** pathogens can produce toxins. cholera can produce toxins that lead to excessive water loss from the lining of the intestines. ##**lifestyle & health** 1) risk, 2) lifestyle choice and cancer, 3) lifestyle choice and coronary heart disease, 4) reducing risk of cancer and CHD